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Interaction between the level of immunoglobulins and number of somatic cells as a factor shaping the immunomodulating properties of colostrum

Puppel, Kamila; Gołębiewski, Marcin; Ślósarz, Jan; Grodkowski, Grzegorz; Solarczyk, Paweł; Kostusiak, Piotr; Grodkowska, Kinga; Balcerak, Marek and Sakowski, Tomasz (2021) Interaction between the level of immunoglobulins and number of somatic cells as a factor shaping the immunomodulating properties of colostrum. Scientific Reports, 11, p. 15686.

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Document available online at: https://www.nature.com/articles/s41598-021-95283-1


Summary

The aim of this study was to investigate the association between immunoglobulins and SCC as a factor in shaping the content of the immunostimulatory components of colostrum. Seventy-eight multiparous Polish Holstein–Friesian cows were selected for the experiment. Colostrum samples were collected immediately after calving (up to a max. of 2 h). The cows were divided into groups according to the following levels: Immunoglobulins (IG class)—(IG1) over 50 g/L, (IG2) up to 50 g/L; SCC class—(SCC1) up to 400 000/ml, (SCC2) 400–800 000/ml, (SCC3) over 800 000/ml. Colostrum assigned to the IG1 SCC1 group had a statistically significant higher (p ≤ 0.01) concentration of both whey proteins and fatty acids compared to the IG1 SCC2 and SCC3 groups. The concentration of IgG, IgM, and IgA was shown to be higher in IG1 SCC1 than IG2 SCC3 by 226%, 149%, and 115%, respectively. The concentration of lactoferrin was shown to be higher in IG1 SCC1 than IG2 SCC3 by 149%. The determination of colostrum quality based on the concentration of immunoglobulins in the colostrum may not be sufficient because serum IgG concentrations at birth show a linear increase relative to colostrum SCC. A breakdown of colostrum into quality classes, taking into account the level of SCC, should therefore be introduced.


EPrint Type:Journal paper
Keywords:Somatic Cell Count, colostrum properties, Immunoglobulins
Agrovoc keywords:
Language
Value
URI
English
somatic cell count
http://aims.fao.org/aos/agrovoc/c_33554
English
colostrum
http://aims.fao.org/aos/agrovoc/c_1772
English
immunoglobulins
http://aims.fao.org/aos/agrovoc/c_3805
Subjects: Animal husbandry > Production systems > Dairy cattle
Animal husbandry > Health and welfare
Research affiliation: European Union > CORE Organic > CORE Organic Cofund > ProYoungStock
Poland
DOI:10.1038/s41598-021-95283-1
Deposited By: SAKOWSKI, Prof. TOMASZ
ID Code:42365
Deposited On:20 Apr 2022 12:47
Last Modified:20 Apr 2022 12:47
Document Language:English
Status:Published
Refereed:Peer-reviewed and accepted

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