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Accuracy of direct genomic values for functional traits in Brown Swiss cattle

Kramer, M.; Erbe, M.; Seefried, F.R.; Gredler, B.; Bapst, B.; Bieber, A. and Simianer, H. (2014) Accuracy of direct genomic values for functional traits in Brown Swiss cattle. Journal of Dairy Science, 97 (3), pp. 1774-1781.

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Online at: https://www.journalofdairyscience.org/article/S0022-0302(14)00028-9/fulltext

Summary

In this study, direct genomic values for the functional traits general temperament, milking temperament, aggressiveness, rank order in herd, milking speed, udder depth, position of labia, and days to first heat in Brown Swiss dairy cattle were estimated based on ∼777,000 (777k) single nucleotide polymorphism (SNP) information from 1,126 animals. Accuracy of direct genomic values was assessed by a 5-fold cross-validation with 10 replicates. Correlations between deregressed proofs and direct genomic values were 0.63 for general temperament, 0.73 for milking temperament, 0.69 for aggressiveness, 0.65 for rank order in herd, 0.69 for milking speed, 0.71 for udder depth, 0.66 for position of labia, and 0.74 for days to first heat. Using the information of ∼54,000 (54k) SNP led to only marginal deviations in the observed accuracy. Trying to predict the 20% youngest bulls led to correlations of 0.55, 0.77, 0.73, 0.55, 0.64, 0.59, 0.67, and 0.77, respectively, for the traits listed above. Using a novel method to estimate the accuracy of a direct genomic value (defined as correlation between direct genomic value and true breeding value and accounting for the correlation between direct genomic values and conventional breeding values) revealed accuracies of 0.37, 0.20, 0.19, 0.27, 0.48, 0.45, 0.36, and 0.12, respectively, for the traits listed above. These values are much smaller but probably also more realistic than accuracies based on correlations, given the heritabilities and samples sizes in this study. Annotation of the largest estimated SNP effects revealed 2 candidate genes affecting the traits general temperament and days to first heat.


EPrint Type:Journal paper
Keywords:direct genomic value prediction, accuracy of direct genomic value, functional trait, gene annotation, Department of Livestock Sciences, Livestock Breeding, LowInputBreeds
Subjects: Animal husbandry > Production systems > Beef cattle
Animal husbandry > Breeding and genetics
Research affiliation: Switzerland > FiBL - Research Institute of Organic Agriculture Switzerland > Animal Husbandry and Breeding
Germany > University of Göttingen > Animal Breeding and Genetics
European Union > LowInputBreeds > SP 1: Dairy and meat cattle
Switzerland > Other organizations
FP7 Grant Agreement Number:2226232
ISSN:1525-3198
DOI:doi.org/10.3168/jds.2013-7054
Deposited By: Bieber, Anna
ID Code:25080
Deposited On:29 May 2018 07:15
Last Modified:29 May 2018 07:15
Document Language:English
Status:Published
Refereed:Peer-reviewed and accepted

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