home    about    browse    search    latest    help 
Login | Create Account

The A1/A2 β-casein genotype of cows, but not their horn status, influences peptide generation during simulated digestion of milk

Reiche, A.-M.; Martín-Hernández, M. C.; Spengler Neff, A.; Bapst, B.; Fleuti, C.; Dohme-Meier, F.; Hess, H. D.; Egger, L. and Portmann, R. (2024) The A1/A2 β-casein genotype of cows, but not their horn status, influences peptide generation during simulated digestion of milk. Journal of Dairy Science, 107 (9), pp. 6425-6436.

[thumbnail of reiche-etal-2024-JDairySci-Vol207-Issue9-p6425-6436.pdf] PDF - Published Version - English
Available under License Creative Commons Attribution.

2MB

Document available online at: https://www.sciencedirect.com/science/article/pii/S0022030224005745?via%3Dihub


Summary in the original language of the document

The effect of the horn status of cows on their milk composition and quality is a controversial research topic. In this study, 128 milk samples from 64 horned and 64 disbudded Brown Swiss and Original Braunvieh cows were collected from alpine farms where both horned and disbudded cows were grazing on mountain pastures. The samples were analyzed for their detailed composition and protein digestion in a simulated in vitro digestion (INFOGEST). To exclude probable influences on digestion, the β-CN genotype with its variants A1 and A2 was also included in the study. The effects of horn status and β-CN genotype were investigated in linear mixed models, which included additional influencing random factors such as Original Braunvieh blood proportion, stage of lactation, and farm. Horn status did not have any effect on milk composition or digestion. In contrast, milk from A1A1 cows showed a different protein digestion than milk of A1A2 and A2A2 cows in the gastric phase, including smaller amounts of β-casomorphin(BCM)21-associated peptides and larger amounts of BCM11-associated peptides. Abundances of BCM7 did not differ between β-CN genotypes. At the end of the intestinal phase, the digested milk of A1A1 and A2A2 β-CN genotypes did not differ.


EPrint Type:Journal paper
Keywords:beta-casomorphin, horns, in vitro digestion, milk quality, composition, Abacus, FiBL50110
Agrovoc keywords:
Language
Value
URI
English
horns
http://aims.fao.org/aos/agrovoc/c_3665
English
in vitro digestibility
http://aims.fao.org/aos/agrovoc/c_34856
English
milk composition
http://aims.fao.org/aos/agrovoc/c_b0b8d068
English
breeding
http://aims.fao.org/aos/agrovoc/c_49902
Subjects: Animal husbandry > Production systems > Dairy cattle
Research affiliation: Switzerland > Agroscope
Switzerland > FiBL - Research Institute of Organic Agriculture Switzerland > Animal > Animal breeding
Switzerland > Other organizations Switzerland
DOI:10.3168/jds.2024-24403
Related Links:https://www.fibl.org/en/themes/projectdatabase/projectitem/project/1749, https://www.bio-kb-stiere.ch/bio-kb-stiere
Deposited By: Waldmeier, Bernadette
ID Code:55612
Deposited On:08 May 2025 13:32
Last Modified:08 May 2025 13:34
Document Language:English
Status:Published
Refereed:Peer-reviewed and accepted

Repository Staff Only: item control page