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Administration of spruce bark (Picea abies) extracts in young lambs exhibits anticoccidial effects but reduces milk intake and body weight gain

Blomstrand, Berit Marie; Enemark, Heidi L.; Steinshamn, Håvard; Aasen, Inga Marie; Johanssen, Juni Rosann E.; Athanasiadou, Spiridoula; Thamsborg, Stig Milan and Sørheim, Kristin (2022) Administration of spruce bark (Picea abies) extracts in young lambs exhibits anticoccidial effects but reduces milk intake and body weight gain. Acta Veterinaria Scandinavica, 64, pp. 1-10.

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Document available online at: https://actavetscand.biomedcentral.com/articles/10.1186/s13028-022-00629-y


Summary

Background: Eimeria spp. are widespread apicomplexan parasites known to cause coccidiosis in livestock, result- ing in reduced animal welfare and productivity, particularly in sheep. The treatment options are limited, and there is an emerging development of resistance against registered pharmaceuticals. Spruce bark is rich in plant secondary metabolites (PSM), such as condensed tannins, which are bioactive compounds previously shown to have antipara- sitic activity. Here, we examined the anticoccidial properties of bark extract of Norway spruce (Picea abies) against a field isolate of ovine Eimeria spp. by treating Eimeria-infected pre-ruminant lambs with water-extracted bark daily for 12 days. We hypothesised that the bark extract would reduce the faecal oocyst excretion and, consequently, the severity of diarrhoea. Results: Oral administration of spruce bark extract significantly reduced the excretion of Eimeria oocysts in milk-fed lambs post treatment till the end of the trial 22 days post infection. This difference in oocyst excretion between the treated and the untreated infected animals increased with time. Compared to the untreated and the sham-infected control group, the group treated with bark extract had softer fae- ces and reduced milk intake during the treatment period. After discontinuing the treatment, the treated animals got a more solid and formed faeces compared to that of the untreated control group, and the milk intake increased to the level of the sham-infected, untreated control group. The bark extract treated animals had a lower body weight and a lower mean daily body weight gain throughout the whole duration of the experiment. Conclusions: Bark extract from Norway spruce showed marked anticoccidial properties by reducing the faecal oocyst count and associated diarrhoea in young lambs. Simultaneously we experienced detrimental effects of the treatment, displayed as reduced feed intake and daily body weight gain. Therefore, we suggest conducting similar studies with lower bark extract dosage to explore the possibilities of a better trade-off to reduce the negative impact while maintaining the antiparasitic effect. Keywords: Coccidia, Coccidiocide, Eimeria, Industrial by-products, Sheep


EPrint Type:Journal paper
Keywords:Organic PLUS, Bark extracts, coccidiocide, Industrial by-products
Agrovoc keywords:
Language
Value
URI
English
coccidiosis
http://aims.fao.org/aos/agrovoc/c_1705
English
spruce -> Picea
http://aims.fao.org/aos/agrovoc/c_5851
English
young animals
http://aims.fao.org/aos/agrovoc/c_8489
English
lambs
http://aims.fao.org/aos/agrovoc/c_4163
English
side effects
http://aims.fao.org/aos/agrovoc/c_141
English
antiparasitic agents
http://aims.fao.org/aos/agrovoc/c_54ec5e40
English
anticoccidials
http://aims.fao.org/aos/agrovoc/c_497
English
Eimeria
http://aims.fao.org/aos/agrovoc/c_2506
English
bark
http://aims.fao.org/aos/agrovoc/c_820
English
tannins
http://aims.fao.org/aos/agrovoc/c_7606
English
proanthocyanidin
http://aims.fao.org/aos/agrovoc/c_34086
Subjects: Animal husbandry > Production systems > Sheep and goats
Animal husbandry > Health and welfare
Research affiliation: European Union > Horizon 2020 > Organic-PLUS
Norway > NIBIO – Norwegian Institute of Bioeconomy Research
Norway > NORSØK - Norwegian Centre for Organic Agriculture
H2020 or FP7 Grant Agreement Number:774340
DOI:10.1186/s13028-022-00629-y
Deposited By: Blomstrand, Ms Berit Marie
ID Code:44035
Deposited On:06 May 2022 06:23
Last Modified:06 May 2022 06:23
Document Language:English
Status:Published
Refereed:Peer-reviewed and accepted

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