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Pea Albumin 1 Subunit b (PA1b), a Promising Bioinsecticide of Plant Origin.

Gressent, Frédéric; Da Silva, Pedro; Eyraud, Vanessa; Karaki, Lamis and Royer, Corinne (2011) Pea Albumin 1 Subunit b (PA1b), a Promising Bioinsecticide of Plant Origin. Toxins, pp. 1502-17.

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Document available online at: https://hal.archives-ouvertes.fr/hal-00666408


Summary

PA1b (Pea Albumin 1, subunit b) is a peptide extract from pea seeds showing significant insecticidal activity against certain insects, such as cereal weevils (genus Sitophilus), the mosquitoes Culex pipiens and Aedes aegyptii, and certain species of aphids. PA1b has great potential for use on an industrial scale and for use in organic farming: it is extracted from a common plant; it is a peptide (and therefore suitable for transgenic applications); it can withstand many steps of extraction and purification without losing its activity; and it is present in a seed regularly consumed by humans and mammals without any known toxicity or allergenicity. The potential of this peptide to limit pest damage has stimulated research concerning its host range, its mechanism of action, its three-dimensional structure, the natural diversity of PA1b and its structure-function relationships.


EPrint Type:Journal paper
Keywords:insect (en), legumes (en), PA1b (fr), bioinsecticide (fr), toxicology (fr)
Subjects:"Organics" in general
Research affiliation: France > INRAe - Institut national de recherche pour l’agriculture, l’alimentation et l’environnement
ISSN:ISSN: 2072-6651
DOI:10.3390/toxins3121502
Related Links:https://hal.archives-ouvertes.fr/hal-00666408/document
Project ID:HAL-INRAe
Deposited By: PENVERN, Servane
ID Code:41780
Deposited On:12 Aug 2021 10:37
Last Modified:12 Aug 2021 10:37
Document Language:English

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