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Crosstalk between Innate Immunity and Circadian Rhythm: Do fish immune defences have a sense of time?

Lazado, Carlo Cabacang; Lund, Ivar; Skov, Peter V.; Jokumsen, Alfred; Gesto, Manuel; Nguyen, Huy Quang and Pedersen, Per Bovbjerg (2017) Crosstalk between Innate Immunity and Circadian Rhythm: Do fish immune defences have a sense of time? [Krydstale mellem naturlig immunitet og døgnrytme: Har fiske immun forsvars systemer en fornemmelse af tid?] Poster at: European Aquaculture 2017, Dubrovnik, Croatia, 17 - 20 October 2017.

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Summary

Circadian rhythms established by the endogenous clocks enable organisms to anticipate periodic and cyclic changes in their environment. This internal time-keeping system is highly conserved amongst animals and provides them with adaptive advantages as biological processes can be scheduled to occur at the most crucial times of the day. Circadian rhythm is emerging as an important regulator of immune functions. However, there is a paucity of information on the influence of this biological phenomenon in the immune mechanisms of teleost fish. A series of studies was conducted to investigate the circadian rhythms of systemic and mucosal innate immunity using model (i.e., zebrafish, Danio rerio) and non-model (i.e., permit, Trachinotus falcatus; rainbow trout, Oncorhynchus mykiss; tilapia, Oreochromis niloticus) fish species.


Summary translation

Døgnrytme indbygget i det indre ur gør organismer i stand til at tage højde for periodiske og cycliske forandringer i deres miljø. Dette indre “tid-holder” system er godt bevaret hos dyr og udstyrer dem med indbyggede fordele, idet biologiske processer kan “indstilles” til at ske på de mest vigtige tidspunkter af dagen. Døgnrytmer er ved at vise sig som en vigtig faktor i reguleringen af immun funktioner. Der mangler imidlertid viden om betydningen af dette biologiske fænomen i de antimikrobielle faktorer hos benfisk Forsøgets resultater kan have afledt praktisk betydning i forhold til immun-modulering og patogene udfordringer ved at tage højde for den stærke tidsmæssige regulering af medfødt fiske immunitet.

EPrint Type:Conference paper, poster, etc.
Type of presentation:Poster
Keywords:Aquaculture Circadian rhythm Immunity Fish Stress-coping style
Subjects: Knowledge management > Research methodology and philosophy > Specific methods
Animal husbandry > Health and welfare
Research affiliation: Denmark > Organic RDD 2 > RobustFish
Deposited By: Jokumsen, Senior Advisory Scientist Alfred
ID Code:32862
Deposited On:05 Apr 2018 11:15
Last Modified:05 Apr 2018 11:15
Document Language:English
Status:Published
Refereed:Not peer-reviewed

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