?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Alternative+%C3%83%C2%A0+la+chimioth%C3%83%C2%A9rapie+dans+la+ma%C3%83%C2%AEtrise+du+parasitisme+digestif+des+petits+ruminants%3A++R%C3%83%C2%B4le+des+tanins+condens%C3%83%C2%A9s&rft.subject=+Sheep+and+goats&rft.subject=+Health+and+welfare&rft.description=Recent+results+have+shown+that+tanniferous+plants+might+represent+an+alternative+option+to+chemical+drugs+to+control+parasitic+nematodes+of+the+gastrointestinal+tract+in+small+ruminants+since+some+anthelmintic+activity+has+been+associated+with+the+consumption+of+the+plants.%0D%0AThe+2+main+objectives+of+the+project+are+%3A%0D%0A%0D%0A1+to+understand+the+mechanisms+explaining+the+activity+of+tannin+rich++plants+against+nematode+parasites+of+sheep+and+goats%0D%0A%0D%0A2+to+identify++novel+natural+resources+to+exploit+for+non+chemical+control+of+parasite+%0D%0Ain+various+farming+systems%2C+including+organic+farming.+In+particular%2C+the+project+focus+on+potential++industrial+agroressources+%0D%0A%0D%0AIn+vitro+and+in+vivo++assays+++on+parasites++and+on+infected++animals+to+measure+the+anthelmintic+effects%2C+methods+of+histology+and+electron+microscopy+to+examine+the+lesions+induced+by+tannin+to+the+worms%2C+and+biochemical+analysis+of+plant+extracts+or+industrial+agroressources+have+been+used.%0D%0A%0D%0AThe+project+is+still++in+progress.+%0D%0A%0D%0AHowever%2C++the+current+results+indicate+that+%3A+%0D%0A%0D%0A-+condensed+tannins+interfere+both+with+the+main+function++and+structure++of+third+stage+larvae+%0D%0A%0D%0A-+some+industrial+resources+for+tannins+have+been+identified&rft.type=Project+description&rft.type=NonPeerReviewed&rft.identifier=%7BProject%7D+Alternative+%C3%83%C2%A0+la+chimioth%C3%83%C2%A9rapie+dans+la+ma%C3%83%C2%AEtrise+du+parasitisme+digestif+des+petits+ruminants%3A+R%C3%83%C2%B4le+des+tanins+condens%C3%83%C2%A9s.+[Alternatives+to+chemical+drugs+in+the+control+of+gastrointestinal+parasitisim+in+small+ruminants+%3A+role+of+condensed+tannins.]+Runs+2005+-+2007.+Project+Leader(s)%3A+Hoste%2C+Dr+Herv%C3%83%C2%A9%2C+INRA.&rft.relation=http%3A%2F%2Forgprints.org%2F6525%2F