?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Etablierung+der+hom%C3%83%C2%B6opathischen+Mastitistherapie+in+einem+biologisch-dynamisch+wirtschaftenden+Milcherzeugerbetrieb+unter+Ber%C3%83%C2%BCcksichtigung+%C3%83%C2%B6kologischer%2C+epidemiologischer+und+%C3%83%C2%B6konomischer+Gesichtspunkte.%0D%0A&rft.creator=Merck%2C+C.C.&rft.creator=Fidelak%2C+C.&rft.creator=Klocke%2C+P.&rft.creator=Reinecke%2C+A.&rft.creator=Paal%2C+K.&rft.creator=Rothe%2C+J.&rft.creator=Spranger%2C+J.&rft.subject=+Dairy+cattle&rft.subject=+Health+and+welfare&rft.description=6+Summary+The+dairy+cow+mastitis+as+a+disease+with+an+immense+economic+impact+is+widely+spread+in+organic+as+well+as+in+conventional+farms.+Due+to+the+lack+of+alternatives+to+antibiotic+treatment%2C+most+therapeutical+measures+are+based+on+antibiotics+even+in+organic+farms+and+against+common+regulations.+In+contrary+to+these+procedures+the+EU+regulations+(Council+Regulation+EC+1804%2F99)as+well+as+the+consumer%C3%A2%C2%80%C2%99s+anticipation+demand+the+possibly+lowest+levels+of+residual+charges+of+dairy+products+and+environment.+A+two+and+a+half+year+study+in+a+bio-dyn+dairy+herd+in+Brandenburg+(Germany)+with+300+dairy+cows+suffering+from+udder+health+problems+was+conducted+to+evaluate+if+clinical+mastitis+in+dairy+cows+is+to+control+successfully+with+homeopathic+remedies+to+minimize+antibiotic+treatment.+To+assess+the+efficacy+of+the+homeopathic+treatment+the+investigations+are+made+using+a+double+blind+placebo+controlled+study+design+(RCCT).+Using+a+predetermined+treatment+protocol+and+a+certain+diagnostic+pattern+to+match+right+remedies+in+the+sense+of+the+homeopathic+remedy+pictures%2C+the+intention+of+the+chosen+treatment+schedule+was+to+provide+a+very+transparent+concept+which+can+be+used+also+by+unexperienced+veterinarians.+For+treatment+of+acute+mastitis+the+following+remedies+were+used%3A+Phytolacca+D6%2C+Bryonia+D6+%2C+Echinacea+D6+and+Belladonna+D6.+Aconitum+D6+was+added+in+case+of+fever+at+the+beginning+of+disease.+Cases+of+chronical+and+subclinical+mastitis+were+treated+by+Echinacea+D6%2C+Phytolacca+D6+and+Hepar+sulfuris+D8.+In+the+first+part+of+the+study+nearly+all+mastitis+cases+were+treated+only+with+homeopathics+avoiding+antibiotics+strictly.+The+unsatisfying+results+in+this+part+lead+to+a+modification+in+the+second+part+in+which+in+case+of+certain+infections+(S.aureus%2C+Sc.spp.)+a+limited+use+of+antibiotics+was+admitted.+Furthermore%2C+selected+udders+with+subclinical+and+chronical+infections+with+these+kind+of+bacteria+were+dried+off+antibiotically.+Simultaneously+the+farmer+was+engaged+to+intensify+the+efforts+to+optimize+preventive+and+environmental+measures+in+the+herd.++%0D%0A+In+the+second+part+of+the+study+126+cows+(148+quarters)+suffered+from+clinical+mastitis+(Verum%3A+n%3D60%3B+Placebo%3A+n%3D66).+The+cure+rates+were+nearly+identical.+In+the+whole+population+the+clinical+cure+rate+(CCR)+immediately+after+treatment+was+95%25%2C+7+to+8+weeks+after+treatment+65%25.+The+107+clinically+affected+quarters+which+were+infected+by+pathogenic+bacteria+showed+a+bacteriological+cure+rate+(BCR)+of+55%25+each+and+a+complete+bacterio-cytological+cure+rate+(BCCR)+of+35%25+and+40%25+after+4-5+weeks+and+7-8+weeks+after+treatment%2C+respectively.+During+the+observation+time+of+8+weeks+a+total+of+12+cows+in+each+of+the+treatment+groups+produced+a+homologous+recurrent+infection.+6+cows+in+the+verum+group+and+4+cows+in+the+placebo+group+developed+a+new+infection+in+one+of+the+other+quarters.+The+treatment+results+seems+to+be+satisfying+while+the+enhanced+but+still+not+optimized+environmental+conditions+in+the+herd+are+possibly+responsible+for+the+high+amount+of+new+infections+and+recurrences.++%0D%0ALooking+at+the+results+of+the+study+at+all%2C+the+use+of+antibiotics+could+be+decreased+by+75%25+due+to+the+therapy+management+(in+spite+of+the+change+of+it+because+of+unsatisfying+results)+in+combination+with+preventive+measures.+Additionally+the+herd+udder+health+could+be+increased.+So+the+mean+herd+somatic+cell+count+decreased+by+75.000+somatic+cells%2Fml+to+165.000+somatic+cells%2Fml.+Furthermore%2C+the+milk+yield+increased+by+250+kg+to+6.500+kg%2Fcow%2Fyear.+The+count+of+infections+with+S.+aureus+in+the+herd+decreased+dramatically.++%0D%0A%0D%0AThe+decreasing+input+of+antibiotics+in+mastitis+therapy+in+the+project+farm+lead+to+a+decrease+of+36.000+kg+antibiotically+loaded+milk+compared+to+a+hypothetic+conventional+mastitis+management.++%0D%0AFurthermore%2C+the+omission+of+withdrawal+times+after+homeopathic+treatment+resulted+in+a+benefit+of+additional+production+milk+of+25.000+kg.++The+antibiotics+minimizing+therapy+concept+of+the+second+part+of+this+investigation+which+could+be+evaluated+under+practice+conditions+can+be+recommended+for+other+farms+too+if+simultaneous+herd+prevention+measures+can+be+assured+by+the+farm+manager+to+ensure+good+preconditions+for+the+convalescence+of+the+cows.++%0D%0A%0D%0AThe+cure+rates+after+placebo+are+unexpected+high.+Due+to+these+results+it+is+profoundly+debatable+whether+the+strategies+of+conventional+therapy+of+bovine+mastitis+are+suitable+to+ensure+herd+udder+health.+It+should+be+evaluated+which+part+of+the+cure+rate+is+amounted+by+self+cure+and+which+other+factors+have+an+effect+on+the+healing.++The+nearly+identical+cure+rates+in+both+treatment+groups+do+not+allow+the+proof+of+homeopathic+efficacy+at+all.+Indeed%2C+comparing+the+bacteriologically+caused+mastitis+cases+(107+quarters)%2C+there+is+a+significantly+higher+cure+rate+in+the+verum+group+(p+%3C+0.05).&rft.date=2004-08&rft.type=Report&rft.type=NonPeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Forgprints.org%2F6219%2F1%2FBLE_FuE_99UM032_FinalReport.pdf&rft.identifier=Merck%2C+C.C.%3B+Fidelak%2C+C.%3B+Klocke%2C+P.%3B+Reinecke%2C+A.%3B+Paal%2C+K.%3B+Rothe%2C+J.+and+Spranger%2C+J.+(2004)+Etablierung+der+hom%C3%83%C2%B6opathischen+Mastitistherapie+in+einem+biologisch-dynamisch+wirtschaftenden+Milcherzeugerbetrieb+unter+Ber%C3%83%C2%BCcksichtigung+%C3%83%C2%B6kologischer%2C+epidemiologischer+und+%C3%83%C2%B6konomischer+Gesichtspunkte.+[Implementation+of+homeopathic+mastitis+therapy+in+a+bio-dynamic+dairy+farm+regarding+ecological%2C+epidemiological+and+economic+aspects.]+[+Unpublished%2C+]&rft.relation=http%3A%2F%2Forgprints.org%2F6219%2F