?url_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rft.title=Effects+of+Potentised+Substances+on+Growth+Kinetics+of+Saccharomyces+cerevisiae+and+Schizosaccharomyces+pombe&rft.creator=Scherr%2C+Claudia&rft.creator=Baumgartner%2C+Stephan&rft.creator=Spranger%2C+J%C3%83%C2%B6rg&rft.creator=Simon%2C+Meinhard&rft.subject=+Systems+research+and+participatory+research&rft.description=Background%3A+Homeopathic+potencies+are+used+as+specific+remedies+in+complementary+medicine.+Since+the+mode+of+action+is+unknown%2C+the+presumed+specificity+is+discussed+controversially.%0D%0AObjective%3A+This+study+investigated+the+effects+of+potentised+substances+on+two+yeast+species%2C+Saccharomyces+cerevisiae+and+Schizosaccharomyces+pombe%2C+in+a+stable+and+reliable+test+system+with+systematic+negative+controls.+Materials+and+Methods%3A%0D%0AYeast+cells+were+cultivated+in+either+potentised+substances+or+water+controls+in+microplates+and+their+growth+kinetics+were+measured+photometrically.+Water+control+runs+were+performed+repeatedly+to+investigate+the+stability+of+the+experimental+set-up+(systematic+negative+controls).+Results%3A+4+out+of+14+screened+substances+seem+to+have+affected+the+growth+curve+parameters+slope+or+yield.+Out+of+these+substances%2C+azoxystrobin+and+phosphorus+were+chosen+for+8+further+replication+experiments%2C+which+partly+confirmed+the+results+of+the+screening.+On+the+average+of+all+experiments%2C+azoxystrobin+affected+the+slope+of+the+growth+curve+of+Saccharomyces+cerevisiae+(p+%3C+0.05)%2C+and+phosphorus+affected+the+slope+of+the+growth+curve+of+Schizosaccharomyces%0D%0Apombe+(p+%3C+0.05).+No+effects+were+seen+in+the+water+control+runs.+In+addition%2C+significant+interactions+between+treatment+with+potentised+substances+and+experiment+number+were+observed+in+all+experiments+with+potentised+substances+(p+%3C+0.01)%2C+but+not+in+the+water+control+runs.+Conclusions%3A+Both+yeast+species+reacted+to+certain+potentised+substances+by+changing+their+growth+kinetics.+However%2C+the+interactions+found+point+to+additional+factors+of+still+unknown+nature%2C+that+modulate+the+effects+of+potentised+substances.+This+stable+test+system+with+yeasts+may+be+suitable+for+further+studies+regarding+the+efficacy+of+homeopathic+potencies.&rft.publisher=S.+Karger+GmbH%2C+Freiburg&rft.date=2006&rft.type=Journal+paper&rft.type=NonPeerReviewed&rft.format=application%2Fpdf&rft.identifier=http%3A%2F%2Forgprints.org%2F10755%2F1%2FScherr-etal-2006-forsch.komplementaermed.pdf&rft.identifier=Scherr%2C+Claudia%3B+Baumgartner%2C+Stephan%3B+Spranger%2C+J%C3%83%C2%B6rg+and+Simon%2C+Meinhard+(2006)+Effects+of+Potentised+Substances+on+Growth+Kinetics+of+Saccharomyces+cerevisiae+and+Schizosaccharomyces+pombe.+Forschende+Komplement%C3%83%C2%A4rmedizin%2C+13%2C+pp.+298-306.&rft.relation=http%3A%2F%2Forgprints.org%2F10755%2F