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Effect of Consumption of Organically and Conventionally Produced Apples on Antioxidant Activity and DNA Damage in Humans

Briviba, Karlis; Stracke, Berenicke A.; Rüfer, Corinna E.; Watzl, Bernhard; Weibel, Franco P. and Bub, Achim (2007) Effect of Consumption of Organically and Conventionally Produced Apples on Antioxidant Activity and DNA Damage in Humans. J. Agric. Food Chem., 55 (19), pp. 7716-7721.

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Online at: http://pubs.acs.org/cgi-bin/abstract.cgi/jafcau/2007/55/i19/abs/jf0710534.html

Summary

The present study was performed to compare the effects on antioxidant activity and on DNA damage of organic and conventionally produced apples grown under controlled conditions in human peripheral blood lymphocytes. Six healthy volunteers consumed either organically or conventionally grown apples (Golden Delicious, 1000 g) from two neighboring commercial farms in a double-blinded, randomized, cross-over study. The average content of total identified and quantified polyphenols in the organically and conventionally produced apples was 308 and 321 µg/g fresh weight, respectively. No statistically significant differences in the sum of phenolic compounds or in either of the polyphenol classes were found between the agricultural methods. Consumption of neither organically nor conventionally grown apples caused any changes in antioxidant capacity of low-density lipoproteins (lag time test), endogenous DNA strand breaks, Fpg protein-sensitive sites, or capacity to protect DNA against damage caused by hydrogen peroxide. However, a statistically significant decrease in the levels of endonuclease III sensitive sites and an increased capacity to protect DNA against damage induced by iron chloride were determined 24 h after consumption in both groups of either organic or conventionally grown apples, indicating the similar antigenotoxic potential of both organically and conventionally grown apples.


EPrint Type:Journal paper
Keywords:Anbautechnik mehrjährige Kulturen, Innere Qualität, Apple, organic, conventional agricultural methods, antioxidant activity, DNA damage, lymphocytes, BÖL, BOEL, FKZ 04OE027
Subjects: Food systems > Food security, food quality and human health
Crop husbandry > Production systems > Fruit and berries
Research affiliation: Germany > Federal Research Institute of Nutrition and Food - MRI > Department of Physiology and Biochemistry of Nutrition
Germany > Federal Organic Farming Scheme - BOELN > Food > Quality
Switzerland > FiBL - Research Institute of Organic Agriculture Switzerland > Crop Production > Fruit Production
Related Links:http://www.bundesprogramm-oekolandbau.de, http://www.bundesprogramm.de/fkz=04OE027, http://orgprints.org/perl/search/advanced?addtitle%2Ftitle=&keywords=04OE027&projects=BOEL&_order=bypublication&_action_search=Suchen, http://www.fibl.org/forschung/anbautechnik-pflanzenbau/bioobstbau/index.php
Deposited By: Weibel, Franco
ID Code:13339
Deposited On:05 Apr 2008
Last Modified:12 Apr 2010 07:37
Document Language:English
Status:Published
Refereed:Peer-reviewed and accepted

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